Which permeation device measures what?

Field of application is the research of personal protective equipment (PPE)

  • The transport of a substance through personal protective equipment (PPE) to human skin (permeation) should be prevented by wearing PPE.
  • A maximum wearing time depends to a significant extent on the resistance of the personal protective equipment (PPE) to the respective hazardous substance and the type of activity performed.
  • Chemical protective gloves and clothing must therefore have a minimum temporal resistance to the invisible penetration (permeation) of chemicals in accordance with their practical use.
  • This resistance is simulated according to the test method of the standards EN 16523-1:2015-04 and EN 16523-1:2015-04 (formerly DIN EN 374-3) by determining the breakthrough time experimental.
  • The large number of chemical substances, the mandatory recommendation of a suitable PPE material in a chemical safety data sheet, and even the smallest changes in the PPE material composition during manufacture require a large number of permeation tests.

LABC-Labortechnik develops permeation workstations for the standardized performance of meaningful measurements. The standards EN 16523, EN 374, EN 6529 and F-739.

The standards specify lists of test chemicals, known as permeation chemicals. In addition, the appropriate measurement method is given for each permeation chemical. As a rule, the lists are included in the informative annex.

The three different analytical instruments of LABC-Labortechnik cover all permeation chemicals.

List of test chemicals in normative Annex A of EN 374-1:2016

Test Chemicals: CAS: LABC Analyzers:

Qumat®-Q401-EPC with FID-Detektor

Qumat®-Q401-EPC with FID-Detektor

PERMOBIL with PID detector

Fluid-PermCell NW50-liquid

A Methanol 67-56-1 x x
B Acetone 67-64-1 x x
C Acetonitrile 75-05-8 x x
D Dichloromethane 75-09-2 x
E Carbon disulfide 75-15-0 x
F Tuluol 109-88-3 x x
G Diethylamine 109-89-7 x x
H Tetrahydrofuran 109-99-9 x x
I Ethyl acetate 141-78-6 x x
J n-Heptane 142-85-5 x x
K Sodium hydroxide 40 1310-73-2 x
L Sulfuric acid 96 % 7664-93-9 x
M Nitric acid 7967-372 x
N Acetic acid 99 64-19-7 x x x
O Ammonia water 25 1336-21-6 x
P Hydrogen peroxide 30 7722-84-1 x
S Hydrofluoric acid 40 7664-39-3 x
T Formaldehyde 37 % 50-00-0 x

For analysis with hydrogen fluoride and hydrofluoric acid a special top of the NW50liquid cell is recommended.

List of appropriate technique for the detection of chemicals in the informative annex C of EN 16523-1:2015-04

Test Chemicals: CAS: LABC Analyzers:
Qumat®-Q401-EPC mit FID-Detektor Qumat®-Q401-EPC mit FPD-Detektor PERMOBIL mit PID-Detektor Fluid-PermCell NW50-liquid
Methanol 67-56-1 x x
Acetone 67-64-1 x x
Acetonitrile 75-05-8 x x
Dichloromethane 75-09-2 x
Carbon disulfide 75-15-0 x
Tuluol 109-88-3 x x
Diethylamine 109-89-7 x x
Tetrahydrofurnan 109-99-9 x x
Ethyl acetate 141-78-6 x x
n-Heptane 142-78-6 x x
Sodium hydroxide 40 % 1310-73-2 x
Sulfuric acid 96 % 7664-93-9 x
Acetic acid (99 + 1 %) 64-19-7 x x x
Ammonia solution (25 + 1 %) 1336-21-6 x
Hydrogen peroxide (30 + 1 vol. %) 124-43-6 x
Isopropanol 67-63-0 x x
Sodium hypochlorite (13 + 1 % active chlorite) 7681-52-9 x

List of appropriate technique for the detection of gaseous chemicals in informative annex A of EN16523-2:2015-04

Test Chemicals: CAS: LABC Analyzers:
Qumat®-Q401-EPC with FID-Detector Qumat®-Q401-EPC with FPD-Detector PERMOBIL with PID-Detector Fluid-PermCell NW50-liquid
Ammonia NH3 7664-41-7 x
Hydrogen chloride HCl 7647-01-0 x
Chlorine gas Cl2 7782-50-5 x
Ethylene oxide (oxirane) C2H4O 75-21-8 x x
Methyl chloride CHCl 74-97-3 x
Hydrogen fluoride HF 7664-39-3 x
Phosphine PH3 7803-51-2 x
Phosgene COCl2 75-44-5
Methyl bromide CH3Br 74-83-9 x
Carbon monoxide CO 630-08-0
Nitrogen dioxide NO2 10102-44-0 x
Sulfur dioxide SO2 05.09.7446 x x
Sulfuryl fluoride SO2F2 x
1-3 Butadiene 106-99-0 x x
Ozone O3 10028-15-6
Cyanogen chloride ClCn 506-77-4

For the gaseous chemicals, a gas kit for permeation cells is also required. The gas kit is compatible with all LABC permeation cells.